How long must desensitizing agents be used continuously for them to be effective?

Desensitizing agents, which are often used to alleviate dentin hypersensitivity, typically require a period of continuous application to achieve optimal effectiveness. Using these agents for at least two weeks allows sufficient time for the active ingredients to interact with the tooth structure and effectively block the transmission of stimuli that cause sensitivity. During this period, they can help occlude dentinal tubules, reduce nerve excitability, and enhance patient comfort.

While shorter periods of use may offer some benefit, they are usually inadequate for producing significant clinical results. Longer durations, such as three or four weeks, may also enhance effectiveness, but the two-week mark is generally recognized as the minimum duration necessary to start observing positive results.